blyA [2017-8-11 16:0:3]

N-acetylmuramoyl-L-alanine amidase

locus: BSU21410

pI: 9.94

mw: 39.47 kDa

protein length: 367 aa

gene length: 1101 bp

function: SPß-mediated lysis

product: N-acetylmuramoyl-L-alanine amidase

essential: no

ec: 3.5.1.28

synonyms: yomC

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis]
• [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

Gene

Coordinates: 2,263,489 → 2,264,592

The protein

Catalyzed reaction/ biological activity

• Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)

[SW|Domains]

• contains an amidase_2 domain (like [protein|C9C395A5F6A2C06EAC97F228C5C66D1628C937CF|CwlA], [protein|D5612882F1887BE342EF7072E71502382AB7289F|CwlH], [protein|50D7B97E4D3D41F74EF1942B85DE1DA4A33BEBB0|XlyA], [protein|A8AF827637B7208DFA101C9A2911BF9AB1AED08F|XlyB])

Expression and Regulation

Operons

• genes: [gene|C1EB8D05386C1B35B8002239F5247CC6AB25F786|blyA]

  description

  • [pubmed|32419322]

  regulation

  • strongly induced in the presence of salt (1.2 M NaCl) [pubmed|32419322]

References

• 9579063